UltraWellness Key #4: How these small molecules can keep your body from going haywire...

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Welcome to Week Five of our journey to UltraWellness.

This week I'll show you how the small molecules that help keep your body in balance may have gone haywire and are causing your current health problems.

**Remember, I will be launching an entire video course on the 7 keys to UltraWellness starting tomorrow, Thursday, March 8th.  To sign up for that now, go to website below:

==> http://www.ultrawellness.com/p?i=8

Last week, you learned how keeping your gut and digestive system healthy can clear up many problems you might be having. That's an important key to UltraWellness, but we still have a long way to go.

On to this week's topic:  your hormone and neurotransmitter systems.

So, how are you feeling today?

Do your mood and energy swing up and down?

Do you crave sugar or salt? 

Are you overweight and putting on more and more belly fat? 

If you are a woman, do you have premenstrual syndrome, painful or heavy periods, and low sex drive? 

Are you depressed?  Do you sleep poorly?

Do you feel tired but wired?

Do you rely on coffee in the morning and a few glasses of wine at night just to wake up and calm down every day?

If you answered "yes" to any of these questions, you're not alone! 

In fact, this is how most Americans feel.

Why?

We are living out of harmony with our natural biological rhythms.  

The cause: The small molecules that help keep your body in balance have gone haywire.

These molecules are involved in almost every function of the body, and they are critical to wellbeing. 

They are the hormones-messenger molecules of your endocrine system and  the messenger molecules of our brain and nervous system, called neurotransmitters. 

Understand how and why these systems get out of balance and you will go a long way toward understanding why Americans run around tired, depressed, and overweight!

The hormone and neurotransmitter system is another one of the core systems of the body we must address to achieve UltraWellness.

Today, I'm going to explain why these systems get out of whack -- and how to get them back in balance for good.

First, let's review how they work and why so many of you may feel miserable.

==>  All of our hormones and brain messenger chemicals work together in a symphony. 

The hypothalamus and pituitary glands in your brain are the command and control centers for all the endocrine glands.

They send signals to distant parts of the body to control everything from your stress response through your adrenal glands, your blood sugar balance through your pancreas, your thyroid hormone via your thyroid gland, your sexual behavior and function through your reproductive organs. 

They also control growth, sleep, mood, and much more.

Neurotransmitters send messages throughout the body to every cell and organ and tissue and help you do everything from move your arm to feel happy or sad. 

They are like a finely orchestrated symphony that must work together to keep every thing in balance.   

No wonder these chemicals are so important to good health!

And when they become unbalanced, your health can suffer.

Three major causes of poor health in America today are triggered by unbalanced hormones: too much insulin (from sugar), too much cortisol and adrenalin (from stress), and not enough thyroid hormone. 

==> This week, I'm going to talk about what happens when your insulin gets out of control.

(For a much more detailed and in-depth look at balancing your hormones, fixing your insulin problems and the other 6 keys to UltraWellness, please go to http://www.ultrawellness.com/p?i=8 -- remember, the course starts tomorrow, Thursday.)

Let me tell you about a patient of mine whose story may sound all too familiar to you.

James was a 46-year-old Wall Street executive who came to me for a cardiac stress test.  He was a hard driving, don't-look-up type of guy who was convinced he was dying of heart disease. 

Every day during in the late afternoon, he would experience the sudden onset of sweating, a racing heart, anxiety, and shortness of breath.

In other words, he thought he was going to die! 

He was thick around the middle and after listening to his story and taking one look at him, I said, "You don't eat breakfast do you?" 

"And you feel tired after eating so that is why you skip food during the day - to keep sharp for work, and when you feel like that you go for the vending machine or a soda and get a quick sugar fix and in a few minutes you feel better." 

Shocked, he said, "How did you know?"  

I explained to James that he was fighting with his genes and was insulin resistant, leading to wide swings in blood sugar that were responsible for his symptoms.  

In other words, his hormones were severely out of balance.

He couldn't control his metabolism of carbohydrates because he had too much insulin.

So his blood sugar was out of balance, leading to all his symptoms -- and taking him down the slippery road toward high blood pressure, heart disease, obesity, cancer, brain aging, dementia, and more. 

James is not alone. 

In fact, some 80 million Americans suffer from this condition, called insulin resistance. 

It affects everyone a little differently, but the ultimate consequences are similar. 

Most people with insulin resistance have extra fat around the middle. 

(You can check this yourself by measuring your waist around your belly button and dividing that number by the measurement around your hips. If the result is greater than 0.8, you likely have insulin resistance.)  

However, the only sure way to know is with an insulin response test, which measures blood sugar and insulin levels while you are fasting and then one and two hours after you consume a 75-gram sugar drink. 

So why do so many people have insulin resistance?

The answer is simple.

==> We have strayed from eating in harmony with our genes.

Historically, people ate the equivalent of only 20 teaspoons of sugar a year as a hunter/gatherer species.

These days, we eat a whopping 150 lbs per year per person, or about 1/2 pound each day.  The average schoolboy eats 34 teaspoons of sugar a day! 

What happened?

Well, we evolved in a world without grocery stores, convenience stores, and fast food restaurants.  We had to work for our food and had limited access to refined foods or excess calories. 

In fact, our genes are pre-agricultural.  We only started farming 10,000 years ago and only started refining flour about 200 years ago.   

But with the appearance of 15,000 low-fat, high-sugar, high-calorie foods over the last 15 to 20 years, we have created an epidemic of increasing obesity, diabetes, and heart disease.

You see, your body normally produces insulin in response to food in your stomach, particularly sugar.

We once thought that insulin's only role was to help the sugar enter the cells to be metabolized, transforming the stored energy of the sun (in plant foods) with the oxygen we breathe into the energy we use every day to run our bodies. 

But we now know otherwise.

Now we recognize insulin as a major switching station, or control hormone, for many processes. 

It is a major storage hormone -- fat storage, that is. 

As long as your insulin levels are high, you will fight a losing battle with weight loss. That's because insulin acts on your brain to increase appetite, specifically an appetite for sugar. 

Here is what too much insulin really does to your body and health:

* It increases LDL ("bad") cholesterol, lowers HDL ("good") cholesterol, raises triglycerides, and increases your blood pressure. In fact, insulin resistance causes 50 percent of all reported cases of high blood pressure. 

* It makes your blood sticky and more likely to clot, leading to heart attacks and strokes. 

* It stimulates the growth of cancer cells.

* It increases inflammation and oxidative stress and ages your brain.

* It increases unhealthy homocysteine because sugar consumption decreases your levels of  vitamin B6 and folate.

* It also causes sex hormone problems and can lead to infertility, hair growth where you don't want it, hair loss where you don't want to lose it, acne, low testosterone in men, and more. 

* It also leads to mood disturbances.

Clearly, more insulin isn't a good thing!
 
But there's a lot you can do to solve the problem -- and begin to achieve UltraWellness.

==>  Balancing blood sugar and correcting insulin resistance is well within our reach.

Scientific advances during the last few decades have revealed the solution. 

While there are some new medications that can help, such as Glucophage, Avandia, and Actos, they have side effects and are only a band-aid if you use them alone.

Instead, I recommend following a comprehensive nutritional, exercise and stress management plan.

My goal is to make your metabolism more efficient and to make your cells more intelligent and cooperative, not resistant. 

In other words, you will need much less insulin to accomplish the task of balancing your blood sugar.

You can reset your metabolism of sugar and insulin by stopping the things that knock you off kilter and providing the things that balance your body -- allowing you to thrive.

==>  Here is what to do:

1) Stop eating flour and sugar products, especially high-fructose corn syrup.

2) Don't consume liquid calories like those in soft drinks and mixed drinks. They don't make you feel full, so you eat more all day!

3) Stop eating all processed, junk, and packaged foods.  If it doesn't look like the food your great-great-great grandmother probably ate, then stay away. 

4) Stop eating trans and hydrogenated fats.

5) Slow the rate of sugar uptake from the gut through balancing your meals with healthy protein (nuts, seeds, beans, small wild fish, and organic chicken), healthy carbs (vegetables, fruit, beans, and whole grains), and healthy fats (olive oil, nuts and seeds, avocadoes, and fish oil)

6) Rough it up: Eat plenty of soluble fiber (30 to 50 grams a day)

7) Eat smaller, more frequent meals

8) Get an oil change: Eat more omega-3 fats to fix cell membranes so that they can more readily receive messages from insulin. 

9) Move your body: Exercise improves your cells' ability to work better, respond to insulin better, and burn sugar faster.

10) Relax! Stress reduction also helps improve blood sugar control.

11) Make your cells smarter by increasing your intake of specific nutrients, such as chromium, vanadium, magnesium, vitamin E, biotin, the B vitamins, zinc, bioflavinoids, and some newer compounds, including alpha-lipoic acid, arginine, and carnitine. 

12.) Herbs may also be of benefit. These include Panax ginseng, ginkgo biloba, green tea, fenugreek, gymnena sylvestre, bitter melon, and garlic. 

Try this plan and see how it works for you.

I think you'll find that just balancing this one hormone -- insulin -- can have wide-ranging effects on your health.

Join me next week to continue our journey to UltraWellness, when I'll tell show you how to optimize your detoxification system so you can achieve good health -- and avoid becoming a toxic waste dump.

Now I'd like to hear from you...

Do you have symptoms of insulin resistance?

How does the food you eat seem to influence your mood, weight, and other symptoms?

Have you tried any of the recommendations here? How did they work?

Do you have any other examples of how hormones or neurotransmitters can get out of balance and cause problems?

Please click on the Add a Comment button below to share your thoughts.

To your good health,

Mark Hyman, M.D.

PS - Remember, the more in-depth video course on the 7 Keys to UltraWellness will finally be ready tomorrow, Thursday, but you can sign up right now by going to the link below:

==> http://www.ultrawellness.com/p?i=8

Your information on insulin resistance was very uplifting! It is a great reminder to cut out the junk in our diet and enjoy eating the way we should!

Americans are so progressive, but our eating habits are horrible! It is sad to see so many of our youth overweight.

Thank you for continuing to inform and educate us!

by Anonymous at 09:34 AM on 03/07/07

Hi,

I read Ultrametabolism and i'm going to start the detox phase. Should i take any vitamin supplements in this phase?

Thanks
Greetins from Chile!! :)

Katy

by Anonymous at 09:43 AM on 03/07/07

I seem to have all the symptoms you speak of with the neurostransmitter issues and the insulin resistance....but my eating patterns don't fit the profile. I eat one teaspoon of sugar or honey daily in my moring coffee. That's it in food. I don't eat junk food, processed or canned food or restaurant food. I eat bran for breakfast, lots of organic chicken, grilled or baked, lots of salads, veggies, whole grain breads etc. My only thought is wine, I drink at least two, sometimes three glasses per evening, and I know all fruit is sugar. Would this be enough to mess up my metabolism? I have gained 20 pounds over the last year and a half, my waist has increased from 28 to 32"!
L

by Anonymous at 10:16 AM on 03/07/07

So, in this blog you talk about specific supplements. Is there a brand or a specific multi vitamin that has all of these in it? How do I know where to buy these and what amounts to take?

by Anonymous at 10:43 AM on 03/07/07

My own experience tells me that the content of the posting is absolutely correct. A couple of years ago, I was busting out of 38 inch jeans, my blood pressure was high, and my blood sugar was out of control. I started a program of eating less, eating better and exercising more. Now I'm comfortably in 32 in jeans, my BP is 115/70 and my blood sugar is OK... What else can I say...!

by Anonymous at 11:47 AM on 03/07/07

Hello,

Great post! I definately have these problems. I was on a low carb diet about 5 yrs. ago. I lost 60 lbs. I went off that diet and have gained back that weight and everything I eat turns to fat. I finally found a Dr. from the ACAM list.(acam.org- click on "find a Dr." these are Dr.'s who practice medicine & natural therapies both) list who checked my iodine levels, (by a simple urine test), This also affects metabolism. He put me on Iodoral(a natural form of iodine) and now my cholesteral is quickly going down for the first time in 3 years, and my sleep is getting better too. There are so many things that affect metabolism that we are really begining to find out about because of Dr.'s like Mark Hyman. Now I hope to start losing this weight the real way,with the help of Dr. Hyman's website.!

by Anonymous at 03:29 PM on 03/07/07

I have type 1 diabetes,so have to inject insulin, have kinda eliminated flour,I use stevia,as a sweetener & try to up my fiber intake! Any other suggestions?
Thanks,Sue Wesley

by Anonymous at 04:11 PM on 03/07/07

Your information on all these junk foods is inspiring. Keep teaching us more!

I need to know if I should buy the Omega-3 caps and vitamins supplements.What about bread in the morning when hungry?

by Anonymous at 05:42 AM on 03/08/07

Please Podcast the audio in your videos in audio mp3 format.
People can listen when & where they have extra time. Little is lost vs talking head speech.
Thanks for considering my request and thanks for your offerings.
Bob

by Anonymous at 04:59 PM on 03/08/07

Nevermind...Found the podcasts...I usually get your stuff from email and go to Youtube rather than the blog. Your way ahead of me.
You might mention this in your emails in addition to the video's.
Thanks again.
Bob

by Anonymous at 05:07 PM on 03/08/07

Thanks a lot for validating what I have read in other books and most importantly what I am going through. I have been diagnosed for Hashimoto's disease and Celiac disease. I am implementing what I learned from your blog. God bless you for work in educationg as how to achieve REAL wellness. Unfortunately, I have not received the week 2-4 of your lessons. Is there a way for me to access them. Thanks again.

by Anonymous at 05:18 PM on 03/08/07

I read your book and what you say is so true.I do have a graving for sweets. I love fruit. I like to have a glass of wine in the evening. I have changed my eating habits even thogh I'm 78 yrs. young. I'm now eating as you recommend. I just wish I had read a book like yours 60 yrs. ago and followed the advice. Thanks for the email updates.

by Anonymous at 06:31 PM on 03/09/07

Through reading and following the eating plan in your book I have discovered I am gluten intolerant. Six weeks after starting your plan I had not only lost 13 pounds, but also the all-over bloated feeling, excess gas, stomach discomfort and thickening around the middle that I was experiencing. The puffiness and dark circles under my eyes are gone and I am no longer depressed. I feel terrific, which is my motivation for staying with the plan (including 45 to 60 minutes a day of strength training and yoga). I have read the comments of others and like many of them, I no longer enjoy foods that are bad for me and crave the foods that are good for me. Unfortuately, feeling terrific is not enough motivation for some people. And I am amazed and even saddened that there are so many other people out there with a defeatist attitude. Many of my friends told me the discomforts I was experiencing were a normal part of aging and that I needed to learn to accept it. Wow were they ever wrong!! Your book has shown me caring for my physical self is essential especially as I age. I am 48 and thanks to your book I am not getting older, I'm getting better, and growing old gracefully is not an option but a cop out. THANK YOU!!!!
PS: The only thing I am missing now is conversing with someone I can relate to.

by Anonymous at 10:17 AM on 03/17/07

Hi, I can relate to you and then some. I have been on Synthroid for hypothyroidism for about a year, just a few months ago had my dose upped from 75 to 88. I thought this would eleviate my depression and overall feeling of malaise(just lazy and foggy most of the time) but I am still feeling this way, the hard part for me is getting the energy to do the exercise, I just cant get motivated most of the time. I start out with good intentions and then give up. I will be 47 in September and I too have heard "it's part of getting older".In addition I have the added pressure of raising my 6yr old girl(had at 40!) and 12 yr old boy- most people I know have grown kids. I also weigh about 164 am 5'4"- need to lose 40-50 lbs. So I am going to try to add the good foods and eliminate the bad stuff. Is there anything in particular that really made the biggest change or impact on your overall better health. Have you tried "nutrasystem" I was thinking of trying it, but would love to get an unbiased opinion. Thanks, Janet

by Anonymous at 05:03 PM on 04/09/07

2 years ago i got a copy of the book ultra prevention and I was amazed by the simple things i could do to feel better and to look better. I bought the CDs and have listen to them at least 100 times. I bought the book for my daughter (Medical Student) and some friends too. Last summer I saw the Ultra metabolism book and bought 4 copies for my friends. I now know without even a blood test that I am allergic to gluten. I have lost some weight, but the main change for me is my body composition. I have gone down 2 sizes in my pants. My skin looks great. I have been on very low fat diets for years. Never touched olive oil or did not even know about flex seeds. Now these food items are part of my daily life. This message is for any one who wants to try nutrisystem, don't. Please don't eat package foods. That is the main reason most of us are not healthy these days.

by Anonymous at 11:37 AM on 04/12/07

Congratulations on your weight loss and feeling better. I hope one day to feel better too and lose weight.I am going to buy the book soon.

by Anonymous at 04:02 PM on 04/22/07

Hi Dr. Hyman,

I'd like to know if it would be possible for you to discuss loss of libido in males as a topic. I'm 35 years old and have had this almost complete loss of libido/sex drive for the last 9 years. I went to Dr. Eric Braverman in Manhattan, have seen a local endocrinologist, psychiatrist and a slew of local M.D.'s. I'm told my issues are anxiety related, which I think is right on, however there are a few things that can bring on anxiety--excess E2 can do that, thyroid, adrenal fatigue etc...so I'd like to find the underlying cause, not just fix the symptoms. Also this is very much annoying cause I've lost many years of sexual pleasure, which in and of itself is a great stress busters.

I'd appreciate to know more of what you think about this very issue. I can write more should so you wished, but for now I'll stop here, as I'm not sure this is a topic you will want to discuss on this blog.

Btw, I very much like your approach overall.

Best,
Marc

by Anonymous at 10:21 AM on 08/20/07

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